Chicago Cubs vs Pittsburgh Pirates Prediction – MLB Preview, Picks & Analysis

Chicago Cubs vs Pittsburgh Pirates Prediction - MLB Preview, Picks & Analysis

Chicago Cubs vs. Pittsburgh Pirates Preview: Showdown at Wrigley Field – September 15, 2025

As the MLB regular season winds down, the Chicago Cubs are set to host the Pittsburgh Pirates at Wrigley Field on September 15, 2025. This late-season matchup carries significant implications as both teams look to solidify their playoff aspirations. With the Cubs clinging to a narrow lead in the National League Central and the Pirates battling for a wildcard spot, this game promises high stakes and intense competition.

Standings and Context

The Chicago Cubs enter this game with a record of 85-63, sitting atop the NL Central Division. They’ve maintained a slim margin over the second-place St. Louis Cardinals, making every remaining game pivotal for clinching the division title. The Cubs have shown resilience throughout the season, overcoming injuries and slumps with contributions from both young talent and seasoned veterans.

Meanwhile, the Pittsburgh Pirates, at 81-67, are locked in a dogfight for one of the two National League wildcard spots. They trail the San Francisco Giants by a game for the final playoff position. The Pirates have been one of the surprise teams this season, leveraging a mix of emerging stars and savvy veteran leadership to overachieve expectations.

Recent Performance

Chicago Cubs:
In their last 10 games, the Cubs have posted a 6-4 record, including a recent three-game sweep of the Cincinnati Reds. Their offense has been clicking, averaging 5.7 runs per game over this stretch. Key moments include a come-from-behind victory against the Reds where they scored four runs in the eighth inning to seal the win. However, their bullpen has shown vulnerability, blowing two save opportunities during this period.

Pittsburgh Pirates:
The Pirates have gone 7-3 in their last 10 games, riding a four-game winning streak into this matchup. They recently captured a series victory against the New York Mets, highlighted by a thrilling walk-off win in extra innings. The Pirates’ pitching staff, particularly the bullpen, has been stellar, posting a collective ERA of 2.85 over the past 10 games.

Head-to-Head History

This season, the Cubs and Pirates have faced off 12 times, with the Cubs winning eight of those encounters. Historically, the Cubs have had the upper hand, winning 10 of the last 15 meetings dating back to the previous season. Wrigley Field has been kind to the Cubs in this rivalry, where they’ve won five of the six games played against Pittsburgh this year.

Pitching Matchups

Chicago Cubs:
The Cubs will send right-hander Marcus Stroman to the mound. Stroman has been the anchor of the Cubs’ rotation with a 3.25 ERA, a WHIP of 1.15, and 8.7 strikeouts per nine innings (K/9) this season. His last outing saw him pitch seven innings of two-run ball with eight strikeouts against the Cardinals.

Pittsburgh Pirates:
Opposing him will be the Pirates’ ace, left-hander Mitch Keller. Keller has emerged as a dominant force with a 2.95 ERA, a WHIP of 1.10, and a K/9 of 9.3. He recently pitched a complete game shutout against the Phillies, striking out 10 and further cementing his status as one of the league’s top pitchers.

Key Position-Player Matchups

Chicago Cubs:
1. Cody Bellinger (OF): Batting .285 with an OPS of .850, 28 home runs, and 85 RBIs. Bellinger’s power and plate discipline make him a constant threat, particularly against right-handed pitchers like Keller.

  1. Nico Hoerner (2B): Hitting .295 with an OPS of .820 and 42 stolen bases, Hoerner is the catalyst at the top of the Cubs lineup. His speed and on-base ability will be crucial against Keller’s precision.

Pittsburgh Pirates:
1. Ke’Bryan Hayes (3B): With a .270 average, OPS of .815, 20 homers, and 75 RBIs, Hayes is a key figure in the Pirates lineup. His ability to handle high-velocity pitches will be tested against Stroman.

  1. Oneil Cruz (SS): Batting .265 with an OPS of .828, 22 home runs, and 50 RBIs. Cruz’s combination of power and speed poses a dual threat, and his aggressive approach will challenge Stroman’s finesse.

Situational Factors

The game will be played at Wrigley Field, traditionally a hitter-friendly park, especially when the wind is blowing out. The weather forecast predicts a mild evening with temperatures in the mid-70s and a light wind blowing out to left-center field, which could aid power hitters.

Injuries include Cubs closer Adbert Alzolay, who remains day-to-day with shoulder fatigue, and Pirates catcher Henry Davis, out with a wrist injury. Both absences could significantly impact their respective teams’ strategies.

Advanced Metrics

Chicago Cubs:
wRC+ (Weighted Runs Created Plus): 108, indicating their offense is 8% better than league average, benefiting from a balanced lineup that excels in getting on base and driving in runs. – FIP (Fielding Independent Pitching): Stroman’s FIP is 3.10, suggesting his ERA accurately reflects his quality of pitching, supported by a strong defense.

Pittsburgh Pirates:
WAR (Wins Above Replacement): Mitch Keller boasts a WAR of 5.6, underscoring his significant contribution to the Pirates’ success this season. – Defensive Runs Saved (DRS): The Pirates have a team DRS of +35, highlighting their solid defensive efforts, particularly in the infield.

Prediction

This matchup is a classic pitcher’s duel that could be decided by the bullpens and timely hitting. Given the Cubs’ recent form, home-field advantage, and their historical success against the Pirates this season, I project a narrow victory for the Cubs.

Projected Final Score: Chicago Cubs 4, Pittsburgh Pirates 3
Confidence Level: I’m 65% confident in the Cubs’ victory due to their robust lineup and the familiarity of Wrigley Field, though Keller’s dominant presence on the mound poses a significant hurdle.

As both teams vie for postseason berths, expect a tightly contested and strategically rich game that underscores the drama of September baseball.

Today MLB Pitcher Prop Bets Generator

Player NamePropPredictionLineTrendsLast 3 GamesWindTeamOddsDate
Brandon SproatBrandon Sproat
pitcher_earned_runsOver2.53.0Over Hit 1/1Neutral
New York MetsNew York Mets
-10513-09-2025 (20:10) UTC
Brandon SproatBrandon Sproat
pitcher_strikeoutsOver4.57.0Over Hit 1/1Neutral
New York MetsNew York Mets
-10213-09-2025 (20:10) UTC
Brayan BelloBrayan Bello
pitcher_earned_runsUnder2.52.04Under Hit 1/3Neutral
Boston Red SoxBoston Red Sox
12013-09-2025 (20:10) UTC
Brayan BelloBrayan Bello
pitcher_strikeoutsUnder5.54.38Under Hit 2/3Neutral
Boston Red SoxBoston Red Sox
-15413-09-2025 (20:10) UTC
Bryan WooBryan Woo
pitcher_earned_runsOver1.52.11Over Hit 3/3Neutral
Seattle MarinersSeattle Mariners
-10814-09-2025 (01:40) UTC
Bryan WooBryan Woo
pitcher_strikeoutsUnder7.56.36Under Hit 2/3Neutral
Seattle MarinersSeattle Mariners
-11214-09-2025 (01:40) UTC
Bryce ElderBryce Elder
pitcher_earned_runsOver2.53.28Over Hit 0/3Neutral
Atlanta BravesAtlanta Braves
-12013-09-2025 (23:15) UTC
Bryce ElderBryce Elder
pitcher_strikeoutsOver4.54.44Over Hit 2/3Neutral
Atlanta BravesAtlanta Braves
11313-09-2025 (23:15) UTC
Bubba ChandlerBubba Chandler
pitcher_earned_runsOver2.53.0Over Hit 2/3Neutral
Pittsburgh PiratesPittsburgh Pirates
10013-09-2025 (20:05) UTC
Bubba ChandlerBubba Chandler
pitcher_strikeoutsUnder4.53.0Under Hit 3/3Neutral
Pittsburgh PiratesPittsburgh Pirates
-13813-09-2025 (20:05) UTC
Clayton KershawClayton Kershaw
pitcher_earned_runsUnder2.51.89Under Hit 2/3Neutral
Los Angeles DodgersLos Angeles Dodgers
-15814-09-2025 (01:05) UTC
Clayton KershawClayton Kershaw
pitcher_strikeoutsOver3.53.63Over Hit 2/3Neutral
Los Angeles DodgersLos Angeles Dodgers
-15314-09-2025 (01:05) UTC
Colin ReaColin Rea
pitcher_earned_runsOver2.52.28Over Hit 2/3Bad
Chicago CubsChicago Cubs
11213-09-2025 (18:20) UTC
Colin ReaColin Rea
pitcher_strikeoutsUnder3.53.59Under Hit 2/3Bad
Chicago CubsChicago Cubs
15013-09-2025 (18:20) UTC
Davis MartinDavis Martin
pitcher_earned_runsOver2.52.48Over Hit 2/3Good
Chicago White SoxChicago White Sox
-11313-09-2025 (22:10) UTC
Davis MartinDavis Martin
pitcher_strikeoutsOver3.54.0Over Hit 2/3Good
Chicago White SoxChicago White Sox
-15813-09-2025 (22:10) UTC
Drew RasmussenDrew Rasmussen
pitcher_earned_runsUnder2.51.46Under Hit 2/3Bad
Tampa Bay RaysTampa Bay Rays
-16813-09-2025 (18:20) UTC
Drew RasmussenDrew Rasmussen
pitcher_strikeoutsUnder3.54.18Under Hit 2/3Bad
Tampa Bay RaysTampa Bay Rays
14813-09-2025 (18:20) UTC
Dylan CeaseDylan Cease
pitcher_strikeoutsUnder7.56.72Under Hit 3/3Bad
San Diego PadresSan Diego Padres
11414-09-2025 (00:41) UTC
Hunter BrownHunter Brown
pitcher_earned_runsUnder1.51.5Under Hit 2/3Neutral
Houston AstrosHouston Astros
11913-09-2025 (23:15) UTC
Hunter BrownHunter Brown
pitcher_strikeoutsOver5.56.79Over Hit 2/3Neutral
Houston AstrosHouston Astros
10213-09-2025 (23:15) UTC
Hunter GreeneHunter Greene
pitcher_earned_runsUnder2.51.62Under Hit 2/3Neutral
Cincinnati RedsCincinnati Reds
-12114-09-2025 (02:06) UTC
Hunter GreeneHunter Greene
pitcher_strikeoutsUnder7.57.06Under Hit 2/3Neutral
Cincinnati RedsCincinnati Reds
-12614-09-2025 (02:06) UTC
Jacob MisiorowskiJacob Misiorowski
pitcher_earned_runsOver1.52.08Over Hit 2/3Neutral
Milwaukee BrewersMilwaukee Brewers
-12014-09-2025 (00:15) UTC
Jacob MisiorowskiJacob Misiorowski
pitcher_strikeoutsOver6.56.42Over Hit 2/3Neutral
Milwaukee BrewersMilwaukee Brewers
-12914-09-2025 (00:15) UTC
Janson JunkJanson Junk
pitcher_strikeoutsOver3.53.56Over Hit 1/3Neutral
Miami MarlinsMiami Marlins
-15513-09-2025 (20:10) UTC
Joe RyanJoe Ryan
pitcher_earned_runsOver1.52.07Over Hit 2/3Good
Minnesota TwinsMinnesota Twins
-16113-09-2025 (23:10) UTC
Joe RyanJoe Ryan
pitcher_strikeoutsOver5.56.29Over Hit 2/3Good
Minnesota TwinsMinnesota Twins
-15413-09-2025 (23:10) UTC
Logan WebbLogan Webb
pitcher_earned_runsUnder2.52.13Under Hit 2/3Neutral
San Francisco GiantsSan Francisco Giants
-14014-09-2025 (01:05) UTC
Logan WebbLogan Webb
pitcher_strikeoutsOver5.56.7Over Hit 3/3Neutral
San Francisco GiantsSan Francisco Giants
-10814-09-2025 (01:05) UTC
Luis SeverinoLuis Severino
pitcher_earned_runsOver2.52.92Over Hit 2/3Neutral
Oakland AthleticsOakland Athletics
-10314-09-2025 (02:06) UTC
Luis SeverinoLuis Severino
pitcher_strikeoutsUnder5.54.38Under Hit 2/3Neutral
Oakland AthleticsOakland Athletics
-15414-09-2025 (02:06) UTC
Max FriedMax Fried
pitcher_earned_runsUnder2.52.03Under Hit 2/3Neutral
New York YankeesNew York Yankees
-11613-09-2025 (20:10) UTC
Max FriedMax Fried
pitcher_strikeoutsOver5.55.62Over Hit 1/3Neutral
New York YankeesNew York Yankees
-11413-09-2025 (20:10) UTC
Max ScherzerMax Scherzer
pitcher_earned_runsOver2.52.57Over Hit 3/3Neutral
Toronto Blue JaysToronto Blue Jays
12113-09-2025 (19:07) UTC
Max ScherzerMax Scherzer
pitcher_strikeoutsUnder6.55.0Under Hit 2/3Neutral
Toronto Blue JaysToronto Blue Jays
-12313-09-2025 (19:07) UTC
Parker MessickParker Messick
pitcher_earned_runsUnder2.51.25Under Hit 2/3Good
Cleveland GuardiansCleveland Guardians
-15913-09-2025 (22:10) UTC
Parker MessickParker Messick
pitcher_strikeoutsOver4.54.5Over Hit 1/3Good
Cleveland GuardiansCleveland Guardians
-13613-09-2025 (22:10) UTC
Patrick CorbinPatrick Corbin
pitcher_earned_runsUnder2.52.56Under Hit 2/3Neutral
Texas RangersTexas Rangers
10213-09-2025 (20:10) UTC
Patrick CorbinPatrick Corbin
pitcher_strikeoutsOver3.54.41Over Hit 3/3Neutral
Texas RangersTexas Rangers
-18613-09-2025 (20:10) UTC
Ryne NelsonRyne Nelson
pitcher_earned_runsUnder2.51.77Under Hit 2/3Good
Arizona DiamondbacksArizona Diamondbacks
10413-09-2025 (23:10) UTC
Ryne NelsonRyne Nelson
pitcher_strikeoutsUnder4.53.93Under Hit 2/3Good
Arizona DiamondbacksArizona Diamondbacks
10013-09-2025 (23:10) UTC
Sonny GraySonny Gray
pitcher_earned_runsOver2.52.79Over Hit 2/3Neutral
St. Louis CardinalsSt. Louis Cardinals
12814-09-2025 (00:15) UTC
Sonny GraySonny Gray
pitcher_strikeoutsOver5.56.17Over Hit 2/3Neutral
St. Louis CardinalsSt. Louis Cardinals
11914-09-2025 (00:15) UTC
Taijuan WalkerTaijuan Walker
pitcher_earned_runsOver2.51.67Over Hit 3/3Neutral
Philadelphia PhilliesPhiladelphia Phillies
-11613-09-2025 (22:05) UTC
Taijuan WalkerTaijuan Walker
pitcher_strikeoutsUnder2.52.53Under Hit 2/3Neutral
Philadelphia PhilliesPhiladelphia Phillies
13013-09-2025 (22:05) UTC
Tomoyuki SuganoTomoyuki Sugano
pitcher_earned_runsUnder2.52.67Under Hit 0/3Neutral
Baltimore OriolesBaltimore Orioles
11713-09-2025 (19:07) UTC
Tomoyuki SuganoTomoyuki Sugano
pitcher_strikeoutsUnder3.53.56Under Hit 1/3Neutral
Baltimore OriolesBaltimore Orioles
-16613-09-2025 (19:07) UTC

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