MLB Preview: San Francisco Giants vs. Arizona Diamondbacks

Date: September 15, 2025

As the 2025 Major League Baseball season approaches its climax, the San Francisco Giants and the Arizona Diamondbacks are set to clash on September 15th in what promises to be a crucial game with significant playoff implications. Both teams are locked in a competitive National League West race, with only a few games separating them in the standings. This game could play a pivotal role in determining their postseason destinies.

Recent Performance

San Francisco Giants

The Giants enter this matchup riding a wave of momentum, having won seven of their last ten games. This late surge has been powered by an impressive balance of timely hitting and solid pitching. In their most recent series against the Colorado Rockies, the Giants took three out of four games, showcasing their ability to capitalize on scoring opportunities and deliver in high-pressure situations. Key moments included a dramatic walk-off win and a dominant performance from their bullpen, which has been one of the steadiest in the National League.

Arizona Diamondbacks

The Diamondbacks, meanwhile, have faced a slight downturn, losing six of their last ten games. Despite this, they remain within striking distance thanks to a strong earlier season performance. In their recent series against the Los Angeles Dodgers, the Diamondbacks managed to avoid a sweep with a nail-biting extra-innings victory. Their offense has been inconsistent, with standout performances from individual players not always translating into victories. The team’s pitching, especially the bullpen, has shown vulnerability during this recent stretch.

Head-to-Head History

In their season series so far, the Giants have had the upper hand, leading the Diamondbacks 9-7. Historically, the Giants have dominated this matchup, winning 13 of the last 20 meetings over the past two seasons. This trend will certainly weigh on Arizona’s mind as they look to reverse their fortunes and gain ground in the race for the division title.

Pitching Matchups

San Francisco Giants: Logan Webb

Scheduled to start for the Giants is right-hander Logan Webb, who has been a model of consistency throughout the season. With an ERA of 3.22, a WHIP of 1.10, and striking out 8.9 batters per nine innings, Webb has established himself as a reliable ace. In his last outing against the San Diego Padres, he delivered a seven-inning gem, allowing just two hits and one run, further solidifying his role as a key component of the Giants’ rotation. There are no current injury concerns for Webb, which bodes well for San Francisco.

Arizona Diamondbacks: Zac Gallen

The Diamondbacks will counter with their own ace, Zac Gallen. Known for his electric stuff, Gallen boasts a 3.45 ERA, a WHIP of 1.15, and averages 9.7 strikeouts per nine innings. His recent performance, however, has been a mixed bag; in his last start against the Dodgers, he gave up four runs in six innings, struggling with command. Still, Gallen’s overall body of work this year speaks to his potential to dominate, and he will be eager to bounce back against a divisional rival.

Key Position-Player Matchups

San Francisco Giants

1. Brandon Crawford

   Batting average: .278, OPS: .810, Home runs: 15, RBIs: 65
   Crawford has been a consistent force in the Giants’ lineup, especially against right-handed pitching like Zac Gallen. With a wRC+ of 125, Crawford has been instrumental in driving the offense, displaying both power and patience at the plate.

2. Mitch Haniger

   Batting average: .261, OPS: .765, Home runs: 18, RBIs: 70
   Haniger’s ability to deliver in clutch situations will be crucial for the Giants. His past success against Gallen—in which he’s hit .320 over 25 at-bats—could tip the scales in San Francisco’s favor.

Arizona Diamondbacks

1. Ketel Marte

   Batting average: .295, OPS: .850, Home runs: 20, RBIs: 68
   Marte is the spark plug for Arizona’s offense. His wRC+ of 130 indicates his overall offensive contributions, making him a key challenge for Logan Webb and the Giants pitching staff.

2. Christian Walker

   Batting average: .269, OPS: .830, Home runs: 25, RBIs: 85
   Walker is Arizona’s primary power threat. Against Webb, he’s posted a career OPS of .850, suggesting he could be a game-changer in critical situations.

Situational Factors

The game will be held at Oracle Park in San Francisco, known for its pitcher-friendly dimensions. This could potentially benefit both starting pitchers. The weather forecast calls for a mild evening with temperatures in the low 60s and a slight breeze, which should have a minimal impact on gameplay. Injury reports indicate both teams are relatively healthy, with no new major injuries reported.

Advanced Metrics

San Francisco Giants

• FIP (Fielding Independent Pitching): Logan Webb’s FIP of 3.30 suggests that his ERA is very much aligned with his underlying performance, reinforcing his reliability on the mound.
• Offensive WAR (Wins Above Replacement): The Giants’ offensive unit collectively holds a WAR of 35, highlighting their depth and contribution to their winning record.

Arizona Diamondbacks

• FIP: Zac Gallen holds a FIP of 3.40, closely mirroring his ERA, indicating that his pitching performance has been legitimate and not overly reliant on fielding.
• Defensive WAR: Arizona’s defensive prowess is underscored by a defensive WAR of 20, which has been pivotal in their ability to remain competitive throughout the season.

Prediction

Given the Giants’ recent form and their historical advantage over the Diamondbacks, along with Logan Webb’s consistent performances, San Francisco appears to have the upper hand in this matchup. However, the unpredictability of divisional games often adds an element of surprise. I predict a closely contested game with the Giants edging out the Diamondbacks 4-3. My confidence level in this prediction stands at 65%, taking into account both teams’ recent performances and the potential for key players to turn the tide.

Today MLB Pitcher Prop Bets Generator

Player Name	Prop	Prediction	Line	Trends	Last 3 Games	Wind	Team	Odds	Date
Brandon Sproat	pitcher_earned_runs	Over	2.5	3.0	Over Hit 1/1	Neutral	New York Mets	-105	13-09-2025 (20:10) UTC
Brandon Sproat	pitcher_strikeouts	Over	4.5	7.0	Over Hit 1/1	Neutral	New York Mets	-102	13-09-2025 (20:10) UTC
Brayan Bello	pitcher_earned_runs	Under	2.5	2.04	Under Hit 1/3	Neutral	Boston Red Sox	120	13-09-2025 (20:10) UTC
Brayan Bello	pitcher_strikeouts	Under	5.5	4.38	Under Hit 2/3	Neutral	Boston Red Sox	-154	13-09-2025 (20:10) UTC
Bryan Woo	pitcher_earned_runs	Over	1.5	2.11	Over Hit 3/3	Neutral	Seattle Mariners	-108	14-09-2025 (01:40) UTC
Bryan Woo	pitcher_strikeouts	Under	7.5	6.36	Under Hit 2/3	Neutral	Seattle Mariners	-112	14-09-2025 (01:40) UTC
Bryce Elder	pitcher_earned_runs	Over	2.5	3.28	Over Hit 0/3	Neutral	Atlanta Braves	-120	13-09-2025 (23:15) UTC
Bryce Elder	pitcher_strikeouts	Over	4.5	4.44	Over Hit 2/3	Neutral	Atlanta Braves	113	13-09-2025 (23:15) UTC
Bubba Chandler	pitcher_earned_runs	Over	2.5	3.0	Over Hit 2/3	Neutral	Pittsburgh Pirates	100	13-09-2025 (20:05) UTC
Bubba Chandler	pitcher_strikeouts	Under	4.5	3.0	Under Hit 3/3	Neutral	Pittsburgh Pirates	-138	13-09-2025 (20:05) UTC
Clayton Kershaw	pitcher_earned_runs	Under	2.5	1.89	Under Hit 2/3	Neutral	Los Angeles Dodgers	-158	14-09-2025 (01:05) UTC
Clayton Kershaw	pitcher_strikeouts	Over	3.5	3.63	Over Hit 2/3	Neutral	Los Angeles Dodgers	-153	14-09-2025 (01:05) UTC
Colin Rea	pitcher_earned_runs	Over	2.5	2.28	Over Hit 2/3	Bad	Chicago Cubs	112	13-09-2025 (18:20) UTC
Colin Rea	pitcher_strikeouts	Under	3.5	3.59	Under Hit 2/3	Bad	Chicago Cubs	150	13-09-2025 (18:20) UTC
Davis Martin	pitcher_earned_runs	Over	2.5	2.48	Over Hit 2/3	Good	Chicago White Sox	-113	13-09-2025 (22:10) UTC
Davis Martin	pitcher_strikeouts	Over	3.5	4.0	Over Hit 2/3	Good	Chicago White Sox	-158	13-09-2025 (22:10) UTC
Drew Rasmussen	pitcher_earned_runs	Under	2.5	1.46	Under Hit 2/3	Bad	Tampa Bay Rays	-168	13-09-2025 (18:20) UTC
Drew Rasmussen	pitcher_strikeouts	Under	3.5	4.18	Under Hit 2/3	Bad	Tampa Bay Rays	148	13-09-2025 (18:20) UTC
Dylan Cease	pitcher_strikeouts	Under	7.5	6.72	Under Hit 3/3	Bad	San Diego Padres	114	14-09-2025 (00:41) UTC
Hunter Brown	pitcher_earned_runs	Under	1.5	1.5	Under Hit 2/3	Neutral	Houston Astros	119	13-09-2025 (23:15) UTC
Hunter Brown	pitcher_strikeouts	Over	5.5	6.79	Over Hit 2/3	Neutral	Houston Astros	102	13-09-2025 (23:15) UTC
Hunter Greene	pitcher_earned_runs	Under	2.5	1.62	Under Hit 2/3	Neutral	Cincinnati Reds	-121	14-09-2025 (02:06) UTC
Hunter Greene	pitcher_strikeouts	Under	7.5	7.06	Under Hit 2/3	Neutral	Cincinnati Reds	-126	14-09-2025 (02:06) UTC
Jacob Misiorowski	pitcher_earned_runs	Over	1.5	2.08	Over Hit 2/3	Neutral	Milwaukee Brewers	-120	14-09-2025 (00:15) UTC
Jacob Misiorowski	pitcher_strikeouts	Over	6.5	6.42	Over Hit 2/3	Neutral	Milwaukee Brewers	-129	14-09-2025 (00:15) UTC
Janson Junk	pitcher_strikeouts	Over	3.5	3.56	Over Hit 1/3	Neutral	Miami Marlins	-155	13-09-2025 (20:10) UTC
Joe Ryan	pitcher_earned_runs	Over	1.5	2.07	Over Hit 2/3	Good	Minnesota Twins	-161	13-09-2025 (23:10) UTC
Joe Ryan	pitcher_strikeouts	Over	5.5	6.29	Over Hit 2/3	Good	Minnesota Twins	-154	13-09-2025 (23:10) UTC
Logan Webb	pitcher_earned_runs	Under	2.5	2.13	Under Hit 2/3	Neutral	San Francisco Giants	-140	14-09-2025 (01:05) UTC
Logan Webb	pitcher_strikeouts	Over	5.5	6.7	Over Hit 3/3	Neutral	San Francisco Giants	-108	14-09-2025 (01:05) UTC
Luis Severino	pitcher_earned_runs	Over	2.5	2.92	Over Hit 2/3	Neutral	Oakland Athletics	-103	14-09-2025 (02:06) UTC
Luis Severino	pitcher_strikeouts	Under	5.5	4.38	Under Hit 2/3	Neutral	Oakland Athletics	-154	14-09-2025 (02:06) UTC
Max Fried	pitcher_earned_runs	Under	2.5	2.03	Under Hit 2/3	Neutral	New York Yankees	-116	13-09-2025 (20:10) UTC
Max Fried	pitcher_strikeouts	Over	5.5	5.62	Over Hit 1/3	Neutral	New York Yankees	-114	13-09-2025 (20:10) UTC
Max Scherzer	pitcher_earned_runs	Over	2.5	2.57	Over Hit 3/3	Neutral	Toronto Blue Jays	121	13-09-2025 (19:07) UTC
Max Scherzer	pitcher_strikeouts	Under	6.5	5.0	Under Hit 2/3	Neutral	Toronto Blue Jays	-123	13-09-2025 (19:07) UTC
Parker Messick	pitcher_earned_runs	Under	2.5	1.25	Under Hit 2/3	Good	Cleveland Guardians	-159	13-09-2025 (22:10) UTC
Parker Messick	pitcher_strikeouts	Over	4.5	4.5	Over Hit 1/3	Good	Cleveland Guardians	-136	13-09-2025 (22:10) UTC
Patrick Corbin	pitcher_earned_runs	Under	2.5	2.56	Under Hit 2/3	Neutral	Texas Rangers	102	13-09-2025 (20:10) UTC
Patrick Corbin	pitcher_strikeouts	Over	3.5	4.41	Over Hit 3/3	Neutral	Texas Rangers	-186	13-09-2025 (20:10) UTC
Ryne Nelson	pitcher_earned_runs	Under	2.5	1.77	Under Hit 2/3	Good	Arizona Diamondbacks	104	13-09-2025 (23:10) UTC
Ryne Nelson	pitcher_strikeouts	Under	4.5	3.93	Under Hit 2/3	Good	Arizona Diamondbacks	100	13-09-2025 (23:10) UTC
Sonny Gray	pitcher_earned_runs	Over	2.5	2.79	Over Hit 2/3	Neutral	St. Louis Cardinals	128	14-09-2025 (00:15) UTC
Sonny Gray	pitcher_strikeouts	Over	5.5	6.17	Over Hit 2/3	Neutral	St. Louis Cardinals	119	14-09-2025 (00:15) UTC
Taijuan Walker	pitcher_earned_runs	Over	2.5	1.67	Over Hit 3/3	Neutral	Philadelphia Phillies	-116	13-09-2025 (22:05) UTC
Taijuan Walker	pitcher_strikeouts	Under	2.5	2.53	Under Hit 2/3	Neutral	Philadelphia Phillies	130	13-09-2025 (22:05) UTC
Tomoyuki Sugano	pitcher_earned_runs	Under	2.5	2.67	Under Hit 0/3	Neutral	Baltimore Orioles	117	13-09-2025 (19:07) UTC
Tomoyuki Sugano	pitcher_strikeouts	Under	3.5	3.56	Under Hit 1/3	Neutral	Baltimore Orioles	-166	13-09-2025 (19:07) UTC