St.Louis Cardinals vs Tampa Bay Rays Prediction – MLB Preview, Picks & Analysis

St.Louis Cardinals vs Tampa Bay Rays Prediction - MLB Preview, Picks & Analysis

Game Preview: St. Louis Cardinals vs. Tampa Bay Rays, August 22, 2025

Introduction

On August 22, 2025, the St. Louis Cardinals will face off against the Tampa Bay Rays in what promises to be a pivotal matchup as both teams navigate the late-season playoff race. The Cardinals, sitting atop the National League Central, are clinging to a narrow lead as they fend off challengers vying for their spot. Meanwhile, the Rays, who are firmly in the hunt for an American League wildcard berth, look to capitalize on every opportunity to solidify their postseason chances. This interleague matchup not only has significant playoff implications but also offers an intriguing glimpse into how teams from different leagues stack up against one another as the regular season winds down.

Recent Performance

St. Louis Cardinals

Over their last 10 games, the Cardinals have posted a respectable 6-4 record. However, consistency has been an issue, with the team alternating wins and losses in a pattern that suggests they are still searching for a rhythm. Notably, their offense exploded for a 10-2 victory against the Milwaukee Brewers, a game where team ace Jack Flaherty put on a masterful performance. Nonetheless, they dropped two critical games to the Chicago Cubs, underscoring a need to tighten up both offensively and defensively as they push towards the playoffs.

Tampa Bay Rays

The Rays, conversely, have enjoyed a strong stretch, winning 7 of their last 10 contests. A recent sweep of the Boston Red Sox bolstered their wildcard aspirations. The Rays’ pitching staff has been particularly dominant, allowing just nine runs over those three games. Clutch performances by key players, including a walk-off homer from young sensation Wander Franco, have further energized the team. Riding this momentum, the Rays will look to extend their success against the visiting Cardinals.

Head-to-Head History

The Cardinals and Rays have faced each other twice this season, with the Rays emerging victorious on both occasions. Historically, the Rays have had the upper hand, winning 7 of their last 10 meetings against the Cardinals. This trend could give Tampa Bay a psychological edge as they prepare for the upcoming clash.

Pitching Matchups

St. Louis Cardinals: Jack Flaherty

Jack Flaherty (12-8, 3.45 ERA, 1.15 WHIP) is slated to start for the Cardinals. Flaherty has been a cornerstone of the Cardinals’ rotation, exhibiting dominance with a strikeout rate of 9.8 per nine innings. His recent outings have been solid, although he did encounter a hiccup against the Cubs, allowing four runs over six innings. The Cardinals will be hoping for a bounce-back performance from their ace, who has shown a penchant for rising to the occasion in high-pressure games.

Tampa Bay Rays: Shane McClanahan

Starting for the Rays will be Shane McClanahan (14-6, 2.98 ERA, 1.07 WHIP). McClanahan has been one of the American League’s top pitchers this season, boasting an impressive strikeout rate of 10.5 per nine innings. His recent form has been spectacular, highlighted by a complete game shutout against the Yankees. McClanahan’s ability to dominate lineups with his blazing fastball and sharp breaking pitches will be crucial in containing the Cardinals’ offense.

Key Position-Player Matchups

St. Louis Cardinals

  • Nolan Arenado: Batting .292 with an OPS of .854, Arenado has contributed 28 home runs and 89 RBIs. His power and defensive prowess make him a key figure in the Cardinals’ success, although he’ll face a tough matchup against McClanahan’s left-handed pitching.

  • Paul Goldschmidt: Goldschmidt, with a batting average of .278 and a .843 OPS, has hit 25 home runs and driven in 84 RBIs. His ability to maintain a steady on-base presence could pose a challenge to the Rays’ pitching staff.

Tampa Bay Rays

  • Wander Franco: Batting .305 with a .905 OPS, Franco has emerged as a vital component of the Rays’ lineup, with 20 home runs and 81 RBIs. His speed and knack for getting on base will be pivotal against Flaherty.

  • Randy Arozarena: Displaying a .289 average and .870 OPS, Arozarena has been a force with 23 home runs and 78 RBIs. His matchup against Flaherty will be one to watch, as he seeks to exploit any mistakes from the mound.

Situational Factors

The game will take place at Tropicana Field, a venue known for its pitcher-friendly dimensions, which may play a role in the expected low-scoring affair. Weather conditions are inconsequential indoors, allowing teams to focus solely on execution without external factors. Notably, the Cardinals are dealing with a key injury, as starting outfielder Tyler O’Neill remains on the injured list with a strained hamstring, potentially impacting their depth.

Advanced Metrics

St. Louis Cardinals

  • wRC+ (Weighted Runs Created Plus): At 102, slightly above league average, indicating a balanced offensive production anchored by key hitters.
  • FIP (Fielding Independent Pitching): Flaherty’s FIP of 3.60 suggests his ERA might be slightly inflated by defensive lapses.

Tampa Bay Rays

  • WAR (Wins Above Replacement): Franco’s WAR of 5.4 indicates his immense value to the team, both offensively and defensively.
  • xFIP (Expected Fielding Independent Pitching): McClanahan’s xFIP of 2.90 supports his ERA, pointing to sustained high-level performance without reliance on defense.

Prediction

The combination of McClanahan’s dominance on the mound and the Rays’ recent run of form gives them the upper hand in this encounter. While the Cardinals boast firepower, the loss of O’Neill could hamper their lineup’s potential against elite pitching. I predict the Tampa Bay Rays will win a tightly contested game, with a final score of 4-2. My confidence level in this prediction is at 70%, betting on the Rays’ ability to leverage their advantageous head-to-head record and current momentum.

Today MLB Pitcher Prop Bets Generator

Player NamePropPredictionLineTrendsLast 3 GamesWindTeamOddsDate
Aaron NolaAaron Nola
pitcher_earned_runsOver2.53.78Over Hit 2/3Neutral
Philadelphia PhilliesPhiladelphia Phillies
-10508-17
Aaron NolaAaron Nola
pitcher_strikeoutsUnder5.55.78Under Hit 2/3Neutral
Philadelphia PhilliesPhiladelphia Phillies
-12508-17
Aaron NolaAaron Nola
pitcher_walksUnder1.51.78Under Hit 2/3Neutral
Philadelphia PhilliesPhiladelphia Phillies
-17508-17
Andrew AbbottAndrew Abbott
pitcher_earned_runsUnder2.51.57Under Hit 1/3Neutral
Cincinnati RedsCincinnati Reds
-11008-17
Andrew AbbottAndrew Abbott
pitcher_strikeoutsUnder2.55.0Under Hit 1/3Neutral
Cincinnati RedsCincinnati Reds
28008-17
Andrew AbbottAndrew Abbott
pitcher_walksOver1.51.67Over Hit 2/3Neutral
Cincinnati RedsCincinnati Reds
-14508-17
Antonio SenzatelaAntonio Senzatela
pitcher_strikeoutsOver2.52.5Over Hit 2/3Neutral
Colorado RockiesColorado Rockies
11608-17
Clay HolmesClay Holmes
pitcher_earned_runsUnder2.52.17Under Hit 2/3Neutral
New York MetsNew York Mets
-12508-17
Clay HolmesClay Holmes
pitcher_strikeoutsOver3.54.21Over Hit 2/3Neutral
New York MetsNew York Mets
-16508-17
Cristian JavierCristian Javier
pitcher_earned_runsUnder2.52.0Under Hit 1/1Neutral
Houston AstrosHouston Astros
-14508-17
Cristian JavierCristian Javier
pitcher_strikeoutsOver4.55.0Over Hit 1/1Neutral
Houston AstrosHouston Astros
-15408-17
Cristian JavierCristian Javier
pitcher_walksUnder2.52.0Under Hit 1/1Neutral
Houston AstrosHouston Astros
-20008-17
Davis MartinDavis Martin
pitcher_earned_runsUnder3.52.61Under Hit 2/3Neutral
Chicago White SoxChicago White Sox
-16008-17
Davis MartinDavis Martin
pitcher_strikeoutsOver2.53.89Over Hit 2/3Neutral
Chicago White SoxChicago White Sox
-17008-17
Davis MartinDavis Martin
pitcher_walksOver1.51.72Over Hit 3/3Neutral
Chicago White SoxChicago White Sox
-14008-17
Dean KremerDean Kremer
pitcher_earned_runsOver2.52.71Over Hit 2/3Neutral
Baltimore OriolesBaltimore Orioles
-13008-17
Dean KremerDean Kremer
pitcher_strikeoutsOver4.54.83Over Hit 3/3Neutral
Baltimore OriolesBaltimore Orioles
-14608-17
Dean KremerDean Kremer
pitcher_walksUnder1.51.5Under Hit 2/3Neutral
Baltimore OriolesBaltimore Orioles
-13008-17
Garrett CrochetGarrett Crochet
pitcher_earned_runsOver1.51.75Over Hit 3/3Neutral
Boston Red SoxBoston Red Sox
-18508-17
Garrett CrochetGarrett Crochet
pitcher_strikeoutsOver7.57.83Over Hit 2/3Neutral
Boston Red SoxBoston Red Sox
10508-17
Garrett CrochetGarrett Crochet
pitcher_walksUnder1.51.67Under Hit 2/3Neutral
Boston Red SoxBoston Red Sox
-15008-17
George KirbyGeorge Kirby
pitcher_earned_runsUnder2.52.33Under Hit 3/3Neutral
Seattle MarinersSeattle Mariners
-14008-17
George KirbyGeorge Kirby
pitcher_strikeoutsOver5.56.0Over Hit 3/3Neutral
Seattle MarinersSeattle Mariners
11008-17
Janson JunkJanson Junk
pitcher_earned_runsUnder3.52.27Under Hit 2/3Neutral
Miami MarlinsMiami Marlins
-15008-17
Janson JunkJanson Junk
pitcher_strikeoutsOver3.53.47Over Hit 1/3Neutral
Miami MarlinsMiami Marlins
10008-17
Janson JunkJanson Junk
pitcher_walksOver1.50.53Over Hit 1/3Neutral
Miami MarlinsMiami Marlins
17508-17
Javier AssadJavier Assad
pitcher_earned_runsOver1.54.0Over Hit 1/1Good
Chicago CubsChicago Cubs
-17008-17
Javier AssadJavier Assad
pitcher_strikeoutsUnder4.52.0Under Hit 1/1Good
Chicago CubsChicago Cubs
-16008-17
Javier AssadJavier Assad
pitcher_walksUnder1.51.0Under Hit 1/1Good
Chicago CubsChicago Cubs
12008-17
Jeffrey SpringsJeffrey Springs
pitcher_earned_runsUnder2.52.44Under Hit 2/3Neutral
Oakland AthleticsOakland Athletics
-12508-17
Jeffrey SpringsJeffrey Springs
pitcher_strikeoutsOver4.54.36Over Hit 2/3Neutral
Oakland AthleticsOakland Athletics
-13408-17
Jeffrey SpringsJeffrey Springs
pitcher_walksUnder1.51.64Under Hit 3/3Neutral
Oakland AthleticsOakland Athletics
-10508-17
Jose BerriosJose Berrios
pitcher_earned_runsUnder2.52.36Under Hit 2/3Neutral
Toronto Blue JaysToronto Blue Jays
-12508-17
Jose BerriosJose Berrios
pitcher_strikeoutsUnder3.54.76Under Hit 2/3Neutral
Toronto Blue JaysToronto Blue Jays
15508-17
Jose BerriosJose Berrios
pitcher_walksUnder1.51.96Under Hit 2/3Neutral
Toronto Blue JaysToronto Blue Jays
13008-17
Jose QuintanaJose Quintana
pitcher_earned_runsUnder2.52.11Under Hit 2/3Neutral
Milwaukee BrewersMilwaukee Brewers
11508-17
Jose QuintanaJose Quintana
pitcher_strikeoutsUnder2.53.83Under Hit 0/3Neutral
Milwaukee BrewersMilwaukee Brewers
26008-17
Jose QuintanaJose Quintana
pitcher_walksUnder1.52.0Under Hit 2/3Neutral
Milwaukee BrewersMilwaukee Brewers
13008-17
Jose SorianoJose Soriano
pitcher_earned_runsUnder2.52.44Under Hit 2/3Neutral
Los Angeles AngelsLos Angeles Angels
-12508-17
Jose SorianoJose Soriano
pitcher_strikeoutsOver4.55.0Over Hit 2/3Neutral
Los Angeles AngelsLos Angeles Angels
-14508-17
Jose SorianoJose Soriano
pitcher_walksUnder2.52.52Under Hit 3/3Neutral
Los Angeles AngelsLos Angeles Angels
-18008-17
Logan WebbLogan Webb
pitcher_earned_runsOver1.52.28Over Hit 1/3Neutral
San Francisco GiantsSan Francisco Giants
-16508-17
Logan WebbLogan Webb
pitcher_strikeoutsOver5.56.72Over Hit 2/3Neutral
San Francisco GiantsSan Francisco Giants
-14008-17
Logan WebbLogan Webb
pitcher_walksOver1.51.4Over Hit 1/3Neutral
San Francisco GiantsSan Francisco Giants
18008-17
Miles MikolasMiles Mikolas
pitcher_earned_runsUnder2.52.83Under Hit 2/3Neutral
St. Louis CardinalsSt. Louis Cardinals
12008-17
Miles MikolasMiles Mikolas
pitcher_strikeoutsOver3.53.43Over Hit 1/3Neutral
St. Louis CardinalsSt. Louis Cardinals
-12408-17
Miles MikolasMiles Mikolas
pitcher_walksUnder1.51.09Under Hit 3/3Neutral
St. Louis CardinalsSt. Louis Cardinals
-15008-17
Mitchell ParkerMitchell Parker
pitcher_earned_runsOver2.53.29Over Hit 3/3Neutral
Washington NationalsWashington Nationals
-17008-17
Mitchell ParkerMitchell Parker
pitcher_strikeoutsUnder4.53.5Under Hit 3/3Neutral
Washington NationalsWashington Nationals
-16508-17
Mitchell ParkerMitchell Parker
pitcher_walksOver1.52.04Over Hit 2/3Neutral
Washington NationalsWashington Nationals
-12508-17
Nathan EovaldiNathan Eovaldi
pitcher_earned_runsUnder2.51.1Under Hit 2/3Neutral
Texas RangersTexas Rangers
-16508-17
Nathan EovaldiNathan Eovaldi
pitcher_strikeoutsUnder3.55.7Under Hit 1/3Neutral
Texas RangersTexas Rangers
18008-17
Nathan EovaldiNathan Eovaldi
pitcher_walksOver1.51.05Over Hit 1/3Neutral
Texas RangersTexas Rangers
15508-17
Ryan PepiotRyan Pepiot
pitcher_earned_runsOver2.52.44Over Hit 2/3Neutral
Tampa Bay RaysTampa Bay Rays
10008-17
Ryan PepiotRyan Pepiot
pitcher_strikeoutsUnder5.55.52Under Hit 2/3Neutral
Tampa Bay RaysTampa Bay Rays
-13008-17
Ryan PepiotRyan Pepiot
pitcher_walksOver1.51.96Over Hit 3/3Neutral
Tampa Bay RaysTampa Bay Rays
-16008-17
Tyler GlasnowTyler Glasnow
pitcher_earned_runsUnder2.51.64Under Hit 2/3Neutral
Los Angeles DodgersLos Angeles Dodgers
-17008-17
Tyler GlasnowTyler Glasnow
pitcher_strikeoutsOver5.55.82Over Hit 2/3Neutral
Los Angeles DodgersLos Angeles Dodgers
-13008-17
Tyler GlasnowTyler Glasnow
pitcher_walksOver1.52.45Over Hit 3/3Neutral
Los Angeles DodgersLos Angeles Dodgers
-17008-17
Will WarrenWill Warren
pitcher_earned_runsUnder2.52.36Under Hit 3/3Neutral
New York YankeesNew York Yankees
-16008-17
Will WarrenWill Warren
pitcher_strikeoutsUnder5.55.6Under Hit 2/3Neutral
New York YankeesNew York Yankees
-15008-17
Will WarrenWill Warren
pitcher_walksOver1.52.16Over Hit 1/3Neutral
New York YankeesNew York Yankees
-14508-17
Yu DarvishYu Darvish
pitcher_earned_runsUnder2.53.0Under Hit 2/3Neutral
San Diego PadresSan Diego Padres
-11008-17
Yu DarvishYu Darvish
pitcher_strikeoutsOver4.54.14Over Hit 3/3Neutral
San Diego PadresSan Diego Padres
10008-17
Yu DarvishYu Darvish
pitcher_walksUnder1.51.57Under Hit 2/3Neutral
San Diego PadresSan Diego Padres
13008-17

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